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Venice is divided into six (seven) sestieri (singular sestiere) or districts.  The Grand Canal, Venice's main thoroughfare, bifurcates the city. 
San Marco Sestiere, harboring the grand palazzos and government offices of the ruling elite.

Dorsoduro Sestiere, the academic quarter and a hub of Venetian nightlife.

San Polo Sestiere, wealthy dwellings and the grand market: center for all manor of trade.

Santa Croce Sestiere, one of the oldest parts of Venice, with reclaimed swamp in the West. Run down and showing its years.

Cannaregio Sestiere, laborers and workers homes, as well as the Jewish Quarter, fill the narrow streets behind the Grand Canal. Cramped and ruled by gangs.

Castello Sestiere, housing the docks, arsenal and shipyard. Rough taverns.

Giudecca Sestiere, large palaces falling into disrepair and giving way to warehouses and tenements.






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